D245513 Chemical Structure

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Product Description

Catalogue NumberD245513
Chemical Name(-)-2'-Deoxy-3'-oxa-4'-thiocytidine (Apricitabine)
Synonyms2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-, (2R-cis)-; 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.; 4- Amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-2(1H)-pyrimidinone; (-)-2'-Deoxy-3'-oxa-4'-thiocytidine; (-)-BCH 10652; AVX 754; Apricitabine; BCH 10618; SPD 754
CAS Number160707-69-7
Molecular FormulaC₈H₁₁N₃O₃S
Molecular Weight229.25
Category Building Blocks; Chiral Molecules;
Boiling Point475-530°C
Applications(-)-2'-Deoxy-3'-oxa-4'-thiocytidine (Apricitabine) is a drug that is used in the treatment of HIV aids. It as also been shown to be useful against lamivudine and zidovudine resistant virus strains
ReferencesSebastian M., et al.: Org. Proc. Res. & Dev., 265, 763-773 (2011) Ghosh, R., et al.: Expert Opin. Pharmacother., 12, 31-46 (2011)