Deoxynivalenol
| Catalogue number: | D243900 |
| Chemical name: | Deoxynivalenol |
| Synonyms: | (3α,7α)-12,13-Epoxy-3,7,15-trihydroxytrichothec-9-en-8-one; 4-Deoxynivalenol; 4-Desoxynivalenol; DON; Dehydronivalenol; NSC 269144; Vomitoxin; |
| Impurity: | |
| CAS Number: | 51481-10-8 |
| Possible CAS #: | NA |
| Molecular form.: | C₁₅H₂₀O₆ |
| Appearance: | White to Off-White Solid |
| Melting Point: | 145-147°C |
| Mol. Weight: | 296.32 |
| Storage: | -20˚C Freezer |
| Solubility: | Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| Stability: | No Data Available |
| Category: | Chiral Reagents, Inhibitors, Mutagenesis Research Chemicals, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point: | No Data Available |
| Applications: | Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-κB into the nucleus. Environmental contaminants; Food contaminants |
| Dangerous Goods Info: | Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g in the package |
| References: | |
| Peer Review Product Citations: | |
| MSDS: | D243900.pdf |
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