Catalogue number:
D231415
Chemical name:
O-Demethoxypropane Aliskiren
Synonyms:
(αS,γS,δS,ζS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ,3-dihydroxy-4-methoxy-α,ζ-bis(1-methylethyl)benzeneoctanamide; (2S,4S,5S,7S)-5-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-(3-hydroxy-4-methoxybenzyl)-2-isopropyl-8-methylnonanamide
Impurity:
CAS Number:
949925-77-3
Possible CAS #:
NA
Molecular form.:
C₂₆H₄₅N₃O₅
Appearance:
No Data Available
Melting Point:
No Data Available
Mol. Weight:
479.65
Storage:
No Data Available
Solubility:
No Data Available
Stability:
No Data Available
Category:
Amines, Aromatics, Chiral Reagents, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point:
No Data Available
Applications:
O-Demethoxypropane Aliskiren is an impurity of Aliskiren Hemifumarate (A536001), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive.
Dangerous Goods Info:
NA
References:
Kumar, N.U., et. al.: Chem. Biol. Interface, 3, 304 (2013); Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000); Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2002); Wood, J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2003); Grandman, A.H., et al.: Circulation, 111, 1012 (2005)
Peer Review Product Citations:
