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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
5mg | $ 85.00 | 0.0 | |
10mg | $ 120.00 | 0.0 | |
25mg | $ 280.00 | 0.0 | |
50mg | $ 525.00 | 0.0 | |
100mg | $ 930.00 | 0.0 | |
Exact Weight Packaging | $ 145.00 | 0.0 | |
Total | $ 0.0 |
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D231400
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Product Description
Catalogue Number | D231400 |
Chemical Name | Denbufylline |
Synonyms | 1,3-Di-n-butyl-7-[2’-oxopropyl)xanthine; BRL 30892; 1,3-Dibutyl-3,7-dihydro-7-(2-oxopropyl)-1H-purine-2,6-dione; |
CAS Number | 57076-71-8 |
Molecular Formula | C₁₆H₂₄N₄O₃ |
Appearance | White to Pale Beige Solid |
Melting Point | 98-100°C |
Molecular Weight | 320.39 |
Storage | 4°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Category | Standards; Enzyme Activators and Inhibitors; |
Applications | A cell permeable xanthine derivatvie that acts as a selective inhibitor of phosphodiesterase IV (PDE IV). Possesses bronchodilatory properties. Displays negative inotropic effect by acting on a verapamil-sensitive site of the calcium channel in guinea pig ventricle apaillary muscle independently of its PDE inhibitory activity. |
References | Nicholson, C.D., et al.: Br. J. Pharmacol., 97, 889 (1989), Cortijo, J., et al.: Br. J. Pharmacol., 108, 562 (1993), Sanae, F., et al.: J. Pharmacol. Exp. Ther., 277, 54 (1996), Kumari, M., et al.: Br. J. Pharmacol., 121, 459 (1997), |