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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 5mg | $ 80.00 | 0.0 | |
| 10mg | $ 110.00 | 0.0 | |
| 25mg | $ 260.00 | 0.0 | |
| 50mg | $ 495.00 | 0.0 | |
| 100mg | $ 875.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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D231400
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Product Description
| Catalogue Number | D231400 |
| Chemical Name | Denbufylline |
| Synonyms | 1,3-Di-n-butyl-7-[2’-oxopropyl)xanthine; BRL 30892; 1,3-Dibutyl-3,7-dihydro-7-(2-oxopropyl)-1H-purine-2,6-dione; |
| CAS Number | 57076-71-8 |
| Molecular Formula | C₁₆H₂₄N₄O₃ |
| Appearance | White to Pale Beige Solid |
| Melting Point | 98-100°C |
| Molecular Weight | 320.39 |
| Storage | Refrigerator |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Category | Standards; Enzyme Activators and Inhibitors; |
| Applications | A cell permeable xanthine derivatvie that acts as a selective inhibitor of phosphodiesterase IV (PDE IV). Possesses bronchodilatory properties. Displays negative inotropic effect by acting on a verapamil-sensitive site of the calcium channel in guinea pig ventricle apaillary muscle independently of its PDE inhibitory activity. |
| References | Nicholson, C.D., et al.: Br. J. Pharmacol., 97, 889 (1989), Cortijo, J., et al.: Br. J. Pharmacol., 108, 562 (1993), Sanae, F., et al.: J. Pharmacol. Exp. Ther., 277, 54 (1996), Kumari, M., et al.: Br. J. Pharmacol., 121, 459 (1997), |