D231400 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
5mg
$ 80.000.0
10mg
$ 110.000.0
25mg
$ 260.000.0
50mg
$ 495.000.0
100mg
$ 875.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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D231400

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Product Description

Catalogue NumberD231400
Chemical NameDenbufylline
Synonyms1,3-Di-n-butyl-7-[2’-oxopropyl)xanthine; BRL 30892; 1,3-Dibutyl-3,7-dihydro-7-(2-oxopropyl)-1H-purine-2,6-dione;
CAS Number57076-71-8
Molecular FormulaC₁₆H₂₄N₄O₃
AppearanceWhite to Pale Beige Solid
Melting Point98-100°C
Molecular Weight320.39
StorageRefrigerator
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Enzyme Activators and Inhibitors;
ApplicationsA cell permeable xanthine derivatvie that acts as a selective inhibitor of phosphodiesterase IV (PDE IV). Possesses bronchodilatory properties. Displays negative inotropic effect by acting on a verapamil-sensitive site of the calcium channel in guinea pig ventricle apaillary muscle independently of its PDE inhibitory activity.
ReferencesNicholson, C.D., et al.: Br. J. Pharmacol., 97, 889 (1989), Cortijo, J., et al.: Br. J. Pharmacol., 108, 562 (1993), Sanae, F., et al.: J. Pharmacol. Exp. Ther., 277, 54 (1996), Kumari, M., et al.: Br. J. Pharmacol., 121, 459 (1997),