D230710 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
5mg
$ 135.000.0
10mg
$ 250.000.0
50mg
$ 925.000.0
200mg
$ 2270.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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D230710

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Product Description

Catalogue NumberD230710
Chemical NameDelanzomib
Synonyms[(1R)-1-[[(2S,3R)-3-Hydroxy-1-oxo-2-[[(6-phenyl-2-pyridinyl)carbonyl]amino]butyl]amino]-3-methylbutyl]boronic Acid; CEP 18770; CIP 18770; CT 47098; NPH 007098; [(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic Acid;
CAS Number847499-27-8
Molecular FormulaC₂₁H₂₈BN₃O₅
AppearanceWhite to Off-White Solid
Melting Point178-190°C (dec.)
Molecular Weight413.28
StorageHygroscopic, -20°C Freezer, Under Inert Atmosphere
SolubilityAcetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
StabilityHygroscopic
Category Building Blocks; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsDelanzomib is an orally active proteasome inhibitor. Delanzomib has been shown to down-modulate NF-κB, induce apoptosis, inhibit angiogenesis and M-CSF-RANKL-induced osteoclastogenesis.
ReferencesPiva, R. et al.: Blood, 111, 2765 (2008); Sanchez, E. et al.: Br. J. Haematol., 148, 569 (2010);