D228978 Chemical Structure

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1mg
$ 155.000.0
10mg
$ 1210.000.0
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D228978

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Product Description

Catalogue NumberD228978
Chemical NameDeflazacort-d3
Synonyms(11β,16β)-21-(Acetyl-d3-oxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione;
Alternate CAS #Unlabelled: 14484-47-0
Molecular FormulaC25H28D3NO6
AppearanceWhite Solid
Melting Point251-253°C (dec.)
Molecular Weight444.54
Storage-20°C Freezer
SolubilityChloroform (Slightly), Methanol (Slightly)
Category Building Blocks; Steroids; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsDeflazacort-d3, is the labeled analogue of Deflazacort (D228975), a systemic corticosteroid, and a derivative of prednisolone. Used for rheumatoid arthritis and lupus.
ReferencesNathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),