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|Pack Size||Quantity||Price (USD)||Sub Total|
|Exact Weight Packaging||
||$ 75.00 / Vial||0.0|
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Inventory Status : In Stock
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|Chemical Name:||Defluoro Dolutegravir|
|Appearance:||Off-White to Light Brown Solid|
|Melting Point:||>166°C (dec.)|
|Solubility:||DMSO (Slightly), Methanol (Slightly, Heated)|
|Category:||Standards; Enzyme Activators and Inhibitors;|
|Applications:||Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.|