D221705 Chemical Structure

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Product Description

Catalogue NumberD221705
Chemical Name5’-Deshydroxy-5’-methoxy Rotigotine
SynonymsN-Propyl-N-[(2S)-1,2,3,4-tetrahydro-5-methoxy-2-naphthalenyl]-2-thiopheneethanamine; (S)-5-Methoxy-N-propyl-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-amine
CAS Number1148154-91-9
Alternate CAS #125572-93-2
Molecular FormulaC20H27NOS
Molecular Weight329.5
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
Applications5’-Deshydroxy-5’-methoxy Rotigotine is an impurity of Rotigotine (R700700). Rotigotine is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
ReferencesLoschmann, P., et al.: Eur. J. Pharmacol., 166, 373 (1989), Edgar, D., et al.: J. Pharmacol. Exp. Ther., 283, 757 (1997), Ferreira, J., et al.: Lancet, 355, 1333 (2000), Arnulf, I., et al.: Neurology, 58, 1019 (2002), Wisor, J., et al.: Neuroscience, 132, 1027 (2005),