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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 5mg | $ 200.00 | 0.0 | |
| 10mg | $ 375.00 | 0.0 | |
| 25mg | $ 915.00 | 0.0 | |
| 50mg | $ 1585.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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D205065
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Product Description
| Catalogue Number | D205065 |
| Chemical Name | Docetaxel 2'-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether |
| Synonyms | (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4,6-bis[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (αR,βS)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid Ester; |
| CAS Number | 195141-96-9 |
| Molecular Formula | C₆₁H₉₅NO₁₄Si₃ |
| Appearance | White Solid |
| Molecular Weight | 1150.66 |
| Storage | Refrigerator, under inert atmosphere |
| Solubility | Chloroform; Methanol; |
| Category | Building Blocks; Standards; Chiral Molecules; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Docetaxel 2'-tert-Butyldimethylsilyl 7,10-Tris(triethylsilyl) Ether is an intermediate used in the synthesis of 2-Debenzoyl-2-pentenoyldocetaxel (D205050), which is a related compound of Docetaxel (D494420), a chemotherapy drug that exhibits anti-mitotic properties and used for treating various metastatic cancers. |
| References | Yokoyama, G., et al.: Int J Clin Oncol 10, 139 (2005); Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993) |