D205055 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 170.000.0
2.5mg
$ 390.000.0
5mg
$ 750.000.0
10mg
$ 1250.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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D205055

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Product Description

Catalogue NumberD205055
Chemical Name2-Debenzoyl-2-pentenoyldocetaxel 2',7,10-Tris(triethylsilyl) Ether
Molecular FormulaC₅₉H₉₇NO₁₄Si₃
Molecular Weight1128.66
Category Building Blocks; Standards; Chiral Molecules; Miscellaneous; Pharmaceutical/API Drug Impurities/Metabolites;
Applications2-Debenzoyl-2-pentenoyldocetaxel 2',7,10-Tris(triethylsilyl) Ether is an intermediate used in the synthesis of 2-Debenzoyl-2-pentenoyldocetaxel (D205050), which is a related compound of Docetaxel (D494420), a chemotherapy drug that exhibits anti-mitotic properties and used for treating various metastatic cancers.
ReferencesYokoyama, G., et al.: Int J Clin Oncol 10, 139 (2005); Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)