Catalogue number: D193425
Chemical name: Darinaparsin
Synonyms: N-[S-(Dimethylarsino)-N-L-γ-glutamyl-L-cysteinyl]-glycine; Dimethylarsinic Glutathione; ZIO 101; Zinapar; L-γ-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine
CAS Number: 69819-86-9
Possible CAS #: NA
Molecular form.: C₁₂H₂₂AsN₃O₆S
Appearance: White to Off-White Solid
Melting Point: >188°C (dec.)
Mol. Weight: 411.31
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Methanol (Slightly), Water (Slightly)
Stability: No Data Available
Category: Amino Acids & Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Darinaparsin is an arsenic cytotoxin that has been used in pharmacological activities to evaluate the effect on survival an radiosensitivity of tumor cells in vitro under normoxia and hypoxia and in vivo using xenograft models. Darinaparsin has significant and preferential cytotoxic and radiosensitizing effects on solid tumors as compared with normal cells.  Darinaparsin may therefore increase the therapeutic index of radiation therapy and has near term translational potential.
Dangerous Goods Info: NA
Peer Review Product Citations:
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  Pack size Price(USD)
50mg $150.00
500mg $1200.00
  Pack size Price(USD)
250mg $695.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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