D193300 Chemical Structure

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D193300

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Product Description

Catalogue NumberD193300
Chemical NameDAPTA
SynonymsD-Alanyl-L-seryl-L-threonyl-L-threonyl-L-threonyl-L-asparaginyl-L-tyrosyl-L-threoninamide;
CAS Number106362-34-9
Molecular FormulaC35H56N10O15
Molecular Weight856.88
Category Research Tools;
ApplicationsDAPTA is a chemokine receptor 5 (CCR5) antagonist used as a selective viral entry inhibitor for R5 tropic HI-1 strains. Blocks CCR5-mediated monocyte chemotaxis.
ReferencesPolianova, M. et al.: Antiviral. Res., 67, 83 (2005); Ruff. M, et al.: Curr. HIV Res., 1,51 (2003);