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$ 125.00 0.0
$ 1000.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
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Product Description

Catalogue Number: Y100200
Chemical Name: Y 11
Synonyms: 1-(2-Hydroxyethyl)-3,5,7-triaza-1-azoniatricyclo[,7]decane Bromide;
CAS Number: 1086639-59-9
Alternate CAS #: 76044-75-2-free base
Molecular Formula: C₈H₁₇BrN₄O
Molecular Weight: 265.15
Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: Y 11 is a potent inhibitor of focal adhesion kinase (FAK); Y 11 prevents FAK autophosphorylation at the Y397 site (IC50 ~ 50 nM in an in vitro kinase assay). Displays selectivity for FAK over a panel of other kinases (concentration used in assay = 1 μM). Y 11 decreases cell viability in a number of cancer cell lines; blocks colony formation in SW620 and BT474 cell lines.

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