URB754


Catalogue Number: U822000
Chemical Name: URB754
Synonyms: 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazine-4-one;
CAS Number: 86672-58-4
Molecular Formula: C₁₆H₁₄N₂O₂
Appearance: White to Off-White Solid
Melting Point: >202°C (dec.)
Molecular Weight: 266.29
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
Category: Aromatics, Heterocycles, Inhibitors
Applications: URB754 is a potent, noncompetitive inhibitor of MGL, exhibiting an IC50 of 200 nM for the recombinant rat brain enzyme. It inhibits rat brain fatty acyl amide hydrolase (FAAH) less effectively with an IC50 of 32 µM and binds weakly to the rat CB1 receptor with an IC50 of 3.8 µM. It does not inhibit cyclooxygenase-1 (COX-1) or COX-2 at concentrations up to 100 µM. Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
References:

All Products are stable to be shipped at room temperature, unless otherwise specified.
Product Rating
Keywords: Buy 86672-58-4 | Purchase 86672-58-4 | Order 86672-58-4 | 86672-58-4 supplier | 86672-58-4 manufacturer | 86672-58-4 distributor | 86672-58-4 cost

Order Product

  Pack size Price(USD)
5mg $45.00
?
25mg $100.00
?
100mg $365.00
?
  Pack size Price(USD)
10mg $50.00
?
50mg $195.00
?
250mg $695.00
?


Exact Weight Packaging ($75(USD) / Vial)
?
Inventory Status:   In Stock




Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Customers Also Viewed

Bulk Orders

If you require bulk orders or quantities you don't see listed, please click here

Translate »