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Pack Size Quantity Price (USD) Sub Total
1mg
$ 35.00 0.0
5mg
$ 120.00 0.0
10mg
$ 175.00 0.0
100mg
$ 1400.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
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Product Description

Catalogue Number: S255600
Chemical Name: Semagacestat
Synonyms: (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide; LY 450139;
CAS Number: 425386-60-3
Molecular Formula: C₁₉H₂₇N₃O₄
Appearance: White Solid
Melting Point: 213-215°C
Molecular Weight: 361.44
Storage: -20˚C Freezer
Solubility: DMSO (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer's disease (AD).
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