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|Pack Size||Quantity||Price (USD)||Sub Total|
|Exact Weight Packaging||
||$ 75.00 / Vial||0.0|
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Inventory Status : Pending QCShips On: 11/11/2019
Bulk Order Request for R425060
|Synonyms:||Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl] Cyclic (35)-Disulfide; [S-(E)]-N-(3-Hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-L-valine (4-1)-Lactone Cyclic (12)-Disulfide; Antibiotic FR 901228; Chromadax; FK 228; FR 901228; NSC 630176;|
|Appearance:||White to Off-White Solid|
|Storage:||Amber Vial, -20°C Freezer, Under Inert Atmosphere|
|Solubility:||Chloroform (Slightly), Methanol (Slightly)|
|Category:||Standards; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;|
|Applications:||Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.|
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