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|Pack Size||Quantity||Price (USD)||Sub Total|
|Exact Weight Packaging||
||$ 75.00 / Vial||0.0|
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Inventory Status : In Stock
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|Synonyms:||3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide; AP 24534; Iclusig|
|Appearance:||Off-White to Pale Beige Solid|
|Melting Point:||>175°C (dec.)|
|Storage:||Amber Vial, Refrigerator, Under inert atmosphere|
|Solubility:||DMSO (Slightly), Methanol (Slightly)|
|Category:||Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors|
|Applications:||Ponatinib is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor|
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