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Pack Size Quantity Price (USD) Sub Total
1mg
$ 50.00 0.0
5mg
$ 65.00 0.0
10mg
$ 95.00 0.0
25mg
$ 170.00 0.0
50mg
$ 325.00 0.0
100mg
$ 595.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
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Inventory Status : In Stock

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Product Description

Catalogue Number: P688250
Chemical Name: Ponatinib
Synonyms: 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide; AP 24534; Iclusig
CAS Number: 943319-70-8
Molecular Formula: C₂₉H₂₇F₃N₆O
Appearance: Off-White to Pale Beige Solid
Melting Point: >175°C (dec.)
Molecular Weight: 532.56
Storage: Amber Vial, Refrigerator, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Category: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors
Applications: Ponatinib is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor
References
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