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Pack Size Quantity Price (USD) Sub Total
2.5mg
$ 180.00 0.0
10mg
$ 680.00 0.0
25mg
$ 1440.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
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Inventory Status : In Stock

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Product Description

Catalogue Number: P293825
Chemical Name: PF-3644022
Synonyms: (10R)-9,10,11,12-Tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one;
CAS Number: 1276121-88-0
Molecular Formula: C₂₁H₁₈N₄OS
Appearance: Off-White to Yellow Solid
Melting Point: >180°C (dec.)
Molecular Weight: 374.46
Storage: -20°C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly)
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: PF-3644022 is a potent freely reversible ATP-competitive compound that inhibits MK2 activity (Ki = 3 nM) with good selectivity when profiled against 200 human kinases. PF-3644022 is a benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor α production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation.
References
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