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Pack Size Quantity Price (USD) Sub Total
5mg
$ 75.00 0.0
10mg
$ 100.00 0.0
50mg
$ 350.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
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Product Description

Catalogue Number: P218290
Chemical Name: PF 431396
Synonyms: N-[2-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methylmethanesulfonamide; N-Methyl-N-[2-[[[2-[(2-oxo- 2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide; PF 431396;
CAS Number: 717906-29-1
Molecular Formula: C₂₂H₂₁F₃N₆O₃S
Appearance: Gray Solid
Melting Point: >214°C (dec.)
Molecular Weight: 506.5
Storage: -20°C Freezer
Solubility: DMSO (Slightly)
Category: Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: PF 431396 is a dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively). Promotes osteoblast recruitment and activity, and stimulates bone formation in ovariectomized rats.
References
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