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|Pack Size||Quantity||Price (USD)||Sub Total|
|Exact Weight Packaging||$ 75.00 / Vial||0.0|
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|Chemical Name:||L-Methionine [R,S]-Sulfoximine|
|Synonyms:||L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine; (2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic Acid;|
|Appearance:||White to Off-White Solid|
|Melting Point:||>210°C (dec.)|
|Solubility:||Formic Acid, Water|
|Category:||Research Tools; Amino Acids;|
|Applications:||Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.|