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|Pack Size||Quantity||Price (USD)||Sub Total|
|Exact Weight Packaging||$ 75.00 / Vial||0.0|
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|Chemical Name:||Abacavir (1.0 mg/mL in Methanol)|
|Synonyms:||(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol;(1S-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; 1592U89; ABC; Abacavir API;|
|Category:||Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Solutions; Kits;|
|Applications:||Abacavir (Abacavir API) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.|
|Dangerous Goods Info:||Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package|