Catalogue Number: I941800
Chemical Name: IWR-1
Synonyms: rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide;
CAS Number: 1127442-82-3
Molecular Formula: C₂₅H₁₉N₃O₃
Molecular Weight: 409.44
Category: Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: IWR-3 act as inhibitors of Wnt response. It appear that IWR compounds induce stabilization of Axin proteins via a direct interaction, which is a part of the b-catenin destruction complex (consists of Apc, Axin, Ck1 and Gsk3b). Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.

All Products are stable to be shipped at room temperature, unless otherwise specified.
Product Rating
Keywords: Buy 1127442-82-3 | Purchase 1127442-82-3 | Order 1127442-82-3 | 1127442-82-3 supplier | 1127442-82-3 manufacturer | 1127442-82-3 distributor | 1127442-82-3 cost

Order Product

  Pack size Price(USD)
10mg $125.00
  Pack size Price(USD)
100mg $1000.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Currently Back Ordered - Please Request Lead Time

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Customers Also Viewed

Bulk Orders

If you require bulk orders or quantities you don't see listed, please click here

Translate »