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|Pack Size||Quantity||Price (USD)||Sub Total|
|Exact Weight Packaging||
||$ 75.00 / Vial||0.0|
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|Chemical Name:||GSK 2945 Hydrochloride|
|Synonyms:||N-(4-Chloro-2-methylbenzyl)-N-(4-chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine Hydrochloride; N-[(4-Chloro-2-methylphenyl)methyl]-N-[(4-chlorophenyl)methyl]-5-nitro-2-thiophenemethanamine Hydrochloride|
|Alternate CAS #:||Free Base: 1438071-12-5|
|Molecular Formula:||C₂₀H₁₈Cl₂N₂O₂S .HCl|
|Appearance:||Off-White to Light Beige Solid|
|Melting Point:||>79ºC (dec.)|
|Storage:||Hygroscopic, -20°C Freezer, Under inert atmosphere|
|Solubility:||DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)|
|Category:||Research Tools; Molecular Biology;|
|Applications:||GSK 2945 Hydrochloride, is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.|