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Pack Size Quantity Price (USD) Sub Total
5mg
$ 45.00 0.0
10mg
$ 50.00 0.0
50mg
$ 75.00 0.0
100mg
$ 95.00 0.0
250mg
$ 175.00 0.0
1g
$ 350.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
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Product Description

Catalogue Number: F805000
Chemical Name: Fingolimod Hydrochloride
Synonyms: 2-Amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol Hydrochloride; FTY720 Hydrochloride;
CAS Number: 162359-56-0
Alternate CAS #: Free Base: 162359-55-9
Molecular Formula: C₁₉H₃₄ClNO₂
Appearance: White to Off-White Solid
Melting Point: >106°C (dec.)
Molecular Weight: 343.93
Storage: -20°C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: Fingolimod Hydrochloride is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. Fingolimod is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Fingolimod is reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
References
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