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Pack Size Quantity Price (USD) Sub Total
5mg
$ 90.00 0.0
10mg
$ 165.00 0.0
25mg
$ 365.00 0.0
50mg
$ 690.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
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Product Description

Catalogue Number: D435305
Chemical Name: 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile
Synonyms: N-Desmethyl Bousutinib
CAS Number: 380843-81-2
Molecular Formula: C₂₅H₂₇Cl₂N₅O₃
Molecular Weight: 516.42
Category: Building Blocks; Miscellaneous;
Applications: Proteolysis Targeting Chimera (PROTAC) is a novel approach to modern drug development programs that utilizes small compounds to target proteins for ubiquitination and degradation by proteasome. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile is a PROTAC compound, which has the potential to target oncogenic BCR-ABL for degradation. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile has also been employed in ligand-based pharmacophore modelling to identify c-Src inhibitors.
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