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Pack Size Quantity Price (USD) Sub Total
5mg
$ 95.00 0.0
10mg
$ 145.00 0.0
50mg
$ 375.00 0.0
100mg
$ 615.00 0.0
200mg
$ 945.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
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Product Description

Catalogue Number: C781800
Chemical Name: Crenolanib Trifluoroacetic Acid Salt
Synonyms: 1-[2-[5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine Trifluoroacetic Acid Salt; ARO 002 Trifluoroacetic Acid Salt; CP 868596 Trifluoroacetic Acid Salt; [1-[2-[5-(3-Methyloxetan-3-ylmethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-yl]amine Trifluoroacetic Acid Salt;
CAS Number: 1797008-57-1
Alternate CAS #: Free amine: 670220-88-9
Molecular Formula: C₂₈H₃₀F₃N₅O₄
Appearance: Off-White to Pale Yellow Solid
Melting Point: 214-217°C
Molecular Weight: 557.56
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Very Slightly)
Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: Crenolanib (CP-868569) is a tyrosine kinase inhibitor that acts by specifically inhibiting the receptor tyrosine kinases PDGFRα and PDGFRβ. Crenolanib (CP-868569) inhibits the activity of PDGFRα D842V kinase and prevented the phosphorylation of wild type PDGFRα. Crenolanib (CP-868569) possesses potential antineoplastic activity. Crenolanib is believed to suppress PDGFR-related signal transduction pathways leading to the inhibition of tumor angiogenesis and tumor cell proliferation.
References
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