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Pack SizeQuantityPrice (USD)Sub Total
25mg
$ 145.000.0
250mg
$ 1175.000.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total$ 0.0
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Inventory Status : Pending QC

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Product Description

Catalogue Number:C227900
Chemical Name:CCT036477
Synonyms:α-(4-Chlorophenyl)-2-methyl-N-2-pyridinyl-1H-indole-3-methanamine;
CAS Number:305372-78-5
Molecular Formula:C₂₁H₁₈ClN₃
Appearance:Off-White to Pale Beige Solid
Melting Point:>167°C (dec.)
Molecular Weight:347.84
Storage:Amber Vial, Refrigerator, Under inert atmosphere
Solubility:DMSO (Slightly), Ethyl Acetate (Slightly)
Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:CCT036477 is an inhibitor of Wnt signaling. Studies show that CCT036477 does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.
References