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$ 290.00 0.0
$ 1260.00 0.0
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Product Description

Catalogue Number: C125400
Chemical Name: Calcein AM
Synonyms: N,N'-[[3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1'-Bis[(acetyloxy) methyl] Ester; Calcein Acetoxymethyl Ester; NSC 689290;
CAS Number: 890090-35-4
Alternate CAS #: Component: 148504-34-1
Molecular Formula: C₄₆H₄₆N₂O₂₃
Appearance: Off-White to Pale Beige Solid
Melting Point: >44°C (dec.)
Molecular Weight: 994.86
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Category: Standards; Fluorescent Reagents; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.