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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 130.000.0
5mg
$ 265.000.0
10mg
$ 375.000.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total$ 0.0
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Inventory Status : In Stock

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Product Description

Catalogue Number:B197005
Chemical Name:cis-4-​[[2-​(1H-​Benzimidazol-​6-​ylamino)​-​8-​quinazolinyl]​oxy]​-​cyclohexanol
Synonyms:NCB-​0846
CAS Number:1792999-26-8
Molecular Formula:C₂₁H₂₁N₅O₂
Appearance:Off-White to Light Yellow Solid
Molecular Weight:375.42
Storage:-20°C Freezer
Solubility:DMSO (Slightly), Methanol (Slightly)
Category: Standards; Enzyme Activators and Inhibitors;
Applications:cis-4-​[[2-​(1H-​Benzimidazol-​6-​ylamino)​-​8-​quinazolinyl]​oxy]​-​cyclohexanol inhibits Traf2 and Nck-interacting protein kinase (TNIK). TNIK is involved with Canonical Wnt/b-catenin signalling, which has regulatory roles in maintaining intestinal stem cells and aberration in this pathway has been implicated in colorectal carcinogenesis. TNIK is a therapeutic target.
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