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Pack Size Quantity Price (USD) Sub Total
100µg
$ 45.00 0.0
1mg
$ 50.00 0.0
10mg
$ 60.00 0.0
25mg
$ 95.00 0.0
100mg
$ 350.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
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Product Description

Catalogue Number: A549650
Chemical Name: 17-(Allylamino) Geldanamycin
Synonyms: 17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)-17-desmethylgeldanamycin; 17-Demethoxy-17-allylaminogeldanamycin; 17AAG; CP 127374; KOS 953; NSC 330507; Tanespimycin; 17-AAG
CAS Number: 75747-14-7
Molecular Formula: C₃₁H₄₃N₃O₈
Appearance: Dark Purple to Very Dark Red Solid
Melting Point: >194°C (dec.)
Molecular Weight: 585.69
Storage: -20°C Freezer, Under Inert Atmosphere
Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Category: Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications: Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.
References
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