Abacavir Triphosphate TEA Salt


Catalogue number: A105045
Chemical name: Abacavir Triphosphate TEA Salt
Synonyms: P-[[(2S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopenten-1-yl]methyl]ester Triphosphate TEA Salt
Impurity:
CAS Number: NA
Alternate CAS #: Free acid: 137820-58-7
Molecular form.: C₁₄H₂₁N₆O₁₀P₃ • xC ₆H₁₅N
Appearance: Off-White Solid
Melting Point: >104C (dec.)
Mol. Weight: 526.2710119
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Methanol (Slightly), Water (Slightly)
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Abacavir Triphosphate TEA Salt, is a metabolite of Abacavir. Abacavir is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Dangerous Goods Info: NA
References:

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: A105045.pdf
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  Pack size Price(USD)
1mg $175.00
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  Pack size Price(USD)
10mg $1400.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   Pending QC




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