Abacavir Triphosphate TEA Salt

Catalogue Number: A105045
Chemical Name: Abacavir Triphosphate TEA Salt
Synonyms: P-[[(2S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopenten-1-yl]methyl]ester Triphosphate TEA Salt
Alternate CAS #: Free acid: 137820-58-7
Molecular Formula: C₁₄H₂₁N₆O₁₀P₃ • xC ₆H₁₅N
Appearance: Off-White Solid
Melting Point: >104C (dec.)
Molecular Weight: 526.2710119
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Methanol (Slightly), Water (Slightly)
Applications: Abacavir Triphosphate TEA Salt, is a metabolite of Abacavir. Abacavir is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: A105045.pdf
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  Pack size Price(USD)
1mg $175.00
  Pack size Price(USD)
10mg $1400.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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