Have a question about this product Click here.

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack Size Quantity Price (USD) Sub Total
$ 125.00 0.0
$ 1000.00 0.0
Exact Weight Packaging
$ 75.00 / Vial 0.0
Total $ 0.0
Request another packsize ? Click here.

Inventory Status : Currently Back Ordered - Please Request Lead Time

Bulk Order Request for A105035

# Pack Size Unit Quantity

Product Description

Catalogue Number: A105035
Chemical Name: Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine
Synonyms: N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir USP Related Compound D; Abacavir EP Impurity B; ; Abacavir Impurities;Abacavir EP Impurity B / USP - D
Impurity: Abacavir EP Impurity B
CAS Number: 1443421-69-9
Molecular Formula: C₁₈H₂₁ClN₁₀O
Molecular Weight: 428.88
Category: Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: Abacavir 5’-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Keywords: Buy 1443421-69-9 | Purchase 1443421-69-9 | Order 1443421-69-9 | 1443421-69-9 supplier | 1443421-69-9 manufacturer | 1443421-69-9 distributor | 1443421-69-9 cost
Translate »