Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester


Catalogue Number: A105030
Chemical Name: Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester
Molecular Formula: C₃₃H₄₆N₆O₁₀
Appearance: Off-White Solid
Molecular Weight: 686.75
Solubility: Chloroform, Dichloromethane, DMSO, Methanol
Category: Amines, Aromatics, Glucuronides, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
References:


All Products are stable to be shipped at room temperature, unless otherwise specified.
Product Rating
Keywords: buy Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester | Purchase Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester | Order Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester |
Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester supplier | Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester manufacturer | Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester distributor | Abacavir 5’-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester cost

Order Product

  Pack size Price(USD)
1mg $140.00
?
  Pack size Price(USD)
10mg $1120.00
?


Exact Weight Packaging ($75(USD) / Vial)
?
Inventory Status:   Pending QC




Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Bulk Orders

If you require bulk orders or quantities you don't see listed, please click here

Translate »