C897545 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
500mg
$ 145.000.0
1g
$ 265.000.0
2.5g
$ 620.000.0
5g
$ 1000.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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C897545

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Product Description

Catalogue NumberC897545
Chemical Name((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane
CAS Number31557-15-0
Molecular FormulaC₇H₁₇ClOSi
AppearanceClear Colorless Oil
Molecular Weight180.75
SolubilityDichloromethane; Ethyl Ether;
Category Building Blocks; Miscellaneous;
Applications((1-Chloro-2-methylpropan-2-yl)oxy)trimethylsilane is an intermediate for the synthesis of 3-Hydroxy Bortezomib (H818150), which is a metabolite of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
ReferencesNawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)