C633550 Chemical Structure

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C633550

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Product Description

Catalogue NumberC633550
Chemical Name(-)-Coclaurine Hydrochloride
Synonyms1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-7-isoquinolinol
CAS Number3422-42-2
Alternate CAS #486-39-5 free base
Molecular FormulaC₁₇H₂₀ClNO₃
AppearanceOff-White to Pale Beige Solid
Melting Point>170°C (dec.)
Molecular Weight321.8
StorageRefrigerator, Under Inert Atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites; Phenethylamines/Amphetamines;
Applications(-)-Coclaurine Hydrochloride is a benzyltetrahydroisoquinoline alkaloid extracted from Magnolia salicifolia. (-)-Coclaurine hydrochloride was shown to block postsynaptic but not presynaptic dopamine receptors in the mouse striatum.
ReferencesWatanabe, H., et al.: J. Pharmacobiodyn., 10, 793 (1983); Roa, K., et al.: J. Sci. Ind. Rsch,, 20B, 125 (1961);