C379967 Chemical Structure

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Product Description

Catalogue NumberC379967
Chemical NameChloroquine-d4 Phosphate Salt
SynonymsN4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine-d4 Phosphate Salt; Aralen-d4 Phosphate Salt; Aralen-d4 Phosphate; Arechin-d4; Avloclor-d4; Bemaphate-d4; Chingamin-d4; Chingamin-d4 Phosphate; SN 7618-d4; Sanoquin-d4;Tanakan-d4;
Alternate CAS #unlabelled: 50-63-5 Diphosphate:1246815-14-4
Molecular FormulaC₁₈H₂₂D₄ClN₃ •xH₃PO₄
AppearanceYellow Solid
Melting Point76-78°C (dec.)
Molecular Weight323.9098
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityDMSO (Sparingly), Methanol (Slightly), Water (Slightly, Sonicated)
Category Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
Boiling PointN/A
ApplicationsLabelled anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. It is a COVID19-related research product.
ReferencesLuthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),