C376665 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
100mg
$ 120.000.0
250mg
$ 270.000.0
500mg
$ 490.000.0
1g
$ 875.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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C376665

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Product Description

Catalogue NumberC376665
Chemical Name((2S,4S)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate
Molecular FormulaC₁₈H₁₇Cl₃O₅S
AppearanceColourless Oil
Molecular Weight451.75
SolubilityDCM, Ethyl Acetate, Methanol
Category Building Blocks; Chiral Molecules;
Applications((2S,4S)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate is an intermediate in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal.
ReferencesHeykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)