(2E)-N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-2-butenamide


Catalogue Number: C365008
Chemical Name: (2E)-N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-2-butenamide
Synonyms: ((E)-4-(Dimethylamino)but-2-enoyl Chloride Compound With (E)-N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
CAS Number: 848133-88-0
Molecular Formula: C₁₈H₁₉ClN₄O₂
Molecular Weight: 358.82
Applications: (2E)-N-(4-Chloro-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-2-butenamide was used in the study for preparation of disubstituted (arylamino)quinolinecarbonitriles as orally active, irreversible inhibitors of human epidermal growth factor receptor-2 kinase activity and antitumor agents.
References:

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