Catalogue number: C292100
Chemical name: CHIR-98014
Synonyms: N6-[2-[[4-(2,4-Dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro- 2,6-pyridinediamine;
CAS Number: 556813-39-9
Possible CAS #: NA
Molecular form.: C₂₀H₁₇Cl₂N₉O₂
Appearance: Yellow Solid
Melting Point: 192-196°C (dec.)
Mol. Weight: 486.31
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: A glycogen synthase kinase-3 (GSK-3) inhibitor. Effects of GSK inhibitors on p-tau, GSK-3β activities and cell death were measured in a human neuronal cell line (LUHMES). Lithium and CHIR98014 reduced tau phosphorylation (Ser396) in the cortex and hippocampus. Inhibition of GSK-3 is recently regarded as one of the viable approaches to therapy for Alzheimer’s disease, cancer, diabetes mellitus, osteoporosis, and bipolar mood disorder.
Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g in the package
Peer Review Product Citations:
MSDS: C292100.pdf
Keywords: Buy 556813-39-9 | Purchase 556813-39-9 | Order 556813-39-9 | 556813-39-9 supplier | 556813-39-9 manufacturer | 556813-39-9 distributor | 556813-39-9 cost

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  Pack size Price(USD)
1mg $55.00
10mg $245.00
50mg $1000.00
  Pack size Price(USD)
5mg $135.00
25mg $550.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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