C291970 Chemical Structure

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C291970

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Product Description

Catalogue NumberC291970
Chemical NameChicoric Acid
Synonyms(2R,3R)-2,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]butanedioic Acid (2R,3R)-2,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]butanedioic Acid; [R-(R*,R*)]-2,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]butanedioic Acid; Bis(3,4-dihydroxycinnamate)tartaric Acid; Chicoric Acid; Cichoric Acid; Dicaffeoyltartaric Acid
CAS Number6537-80-0
Molecular FormulaC₂₂H₁₈O₁₂
AppearancePale Yellow Solid
Melting Point>193°C (dec.)
Molecular Weight474.37
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)
StabilityHygroscopic
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsChicoric Acid is an effective inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. Also a class of cannabinomimetics with CB2 receptor-dependent and independent
ReferencesKing, P. et al.: J. Virol., 72, 8420 (1998); Raduner, S. et al.: J. Biol. Chem., 281, 14192 (2006);