C291900 Chemical Structure

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5g
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10g
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g25
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C291900

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Product Description

Catalogue NumberC291900
Chemical NameChenodeoxycholic Acid
Synonyms(3α,5β,7α)-3,7-Dihydroxycholan-24-oic Acid; (+)-Chenodeoxycholic Acid; 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7α-diol; Chenodeoxycholic Acid; Chenodiol; CDC; Chendol; Chenocol; Fluibil; Ursodeoxycholic Acid EP Impurity A;
ImpurityUrsodeoxycholic Acid EP Impurity A
CAS Number474-25-9
Molecular FormulaC₂₄H₄₀O₄
AppearanceWhite to Pale Beige Solid
Melting Point>112°C (dec.)
Molecular Weight392.57
Storage4°C
SolubilityDioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
Category Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsChenodeoxycholic Acid (Ursodeoxycholic Acid EP Impurity A) is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Facilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.
ReferencesDanzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986),