C281102 Chemical Structure

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1mg
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5mg
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10mg
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C281102

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Product Description

Catalogue NumberC281102
Chemical NameCetirizine-d8 Dihydrochloride
Synonyms2-[4-[(4-Chlorophenyl)-phenylmethyl]-1-piperazinyl-d8]ethoxy]acetic Acid;
CAS Number2070015-04-0
Alternate CAS #Unlabelled: 83881-52-1; Free Base: 774596-22-4
Molecular FormulaC₂₁H₁₉D₈Cl₃N₂O₃
AppearanceWhite to Off-White Solid
Melting Point208-210°C
Molecular Weight469.86
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityMethanol (Slightly), Water (Slightly)
StabilityHygroscopic
Category Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsA nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
ReferencesDe Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)