Fatty Acid Derivatives & Lipids, Glycerols, Inhibitors, Isotope Labelled Compounds, Protein Kinase Inhibitors and Activators
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A biologically active, cell permeable, but nonphysiologic ceramide analog. It stimulates protein phosphatase 2A at concentrations as low as 10 nM and activiates MAP kinase. It induces apoptosis and inhibits glycoproptein traffic by the secretory pathway.