C228800 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
5mg
$ 90.000.0
10mg
$ 125.000.0
25mg
$ 285.000.0
50mg
$ 545.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
  • Request another packsize ? Click here.
  • Inventory Status : In Stock
  • Ships On :
C228800

Bulk Order Request for C228800

#Pack SizeUnitQuantity
1.
2.
3.
4.
5.

Product Description

Catalogue NumberC228800
Chemical NameCDPPB
Synonyms3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide
CAS Number781652-57-1
Molecular FormulaC₂₃H₁₆N₄O
AppearanceWhite to Off-White Solid
Melting Point210-212°C
Molecular Weight364.4
StorageRefrigerator
SolubilityDMSO (Slightly), Ethyl Acetate (Slightly)
Category Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsCDPPB is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that CDPPB suppresses the increase of LDH release and caspase-3 activation induced by traumatic neuronal injury.
ReferencesChen, T. et al.: Neurochem. Res., 37, 983 (2012); Rodriguez, A. et al.: Bioorg. Med. Chem. Lett., 22, 7388 (2012); Gregory, K. et al.: Mol. Pharmacol., 82, 860 (2012)