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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 5mg | $ 100.00 | 0.0 | |
| 10mg | $ 135.00 | 0.0 | |
| 25mg | $ 305.00 | 0.0 | |
| 50mg | $ 580.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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C228800
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Product Description
| Catalogue Number | C228800 |
| Chemical Name | CDPPB |
| Synonyms | 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide |
| CAS Number | 781652-57-1 |
| Molecular Formula | C23H16N4O |
| Appearance | White to Off-White Solid |
| Melting Point | 210-212°C |
| Molecular Weight | 364.4 |
| Storage | Refrigerator |
| Solubility | DMSO (Slightly), Ethyl Acetate (Slightly) |
| Category | Research Tools; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | CDPPB is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that CDPPB suppresses the increase of LDH release and caspase-3 activation induced by traumatic neuronal injury. |
| References | Chen, T. et al.: Neurochem. Res., 37, 983 (2012); Rodriguez, A. et al.: Bioorg. Med. Chem. Lett., 22, 7388 (2012); Gregory, K. et al.: Mol. Pharmacol., 82, 860 (2012) |