C194705 Chemical Structure

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100mg
$ 180.000.0
500mg
$ 920.000.0
1g
$ 1615.000.0
Exact Weight Packaging
$ 95.000.0
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C194705

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Product Description

Catalogue NumberC194705
Chemical Name(+)-Chloro(p-menth-3-yloxy)dimethylsilane
Synonyms[1R-(1α,2β,5α)]-Chlorodimethyl[[5-methyl-2-(1-methylethyl)cyclohexyl]oxy]silane
CAS Number19470-77-0
Molecular FormulaC₁₂H₂₅ClOSi
AppearanceLiquid
Molecular Weight248.86
Category Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications(+)-Chloro(p-menth-3-yloxy)dimethylsilane is a byproduct in the synthesis of Carfilzomib (2R,4R)-Diol (C183525), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
ReferencesFostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);