C176120 Chemical Structure

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50g
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C176120

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Product Description

Catalogue NumberC176120
Chemical NameN-Carbethoxy-4-piperidone
Synonyms1-(Carboethoxy)-4-piperidinone; 1-(Carboethoxy)-4-piperidone; 1-(Ethoxycarbonyl)-4-piperidone; 1-Carbethoxy-4-piperidone; 1-Carbethoxypiperidin-4-one; 1-Ethoxycarbonyl-4-oxopiperidine; 1-Ethoxycarbonyl-4-piperidinone; 4-Oxo-1-piperidinecarboxylic Acid Ethyl eEster; Ethyl 4-Oxo-1-piperidinecarboxylate; N-(Ethoxycarbonyl)-4-piperidone; N-Carbethoxy-4-piperidinone; N-Carboethoxy-4-piperidone; N-Ethoxycarbonyl-4-piperidinone; NSC 139022; Loratadine EP Impurity H
ImpurityLoratadine EP Impurity H
CAS Number29976-53-2
Molecular FormulaC8H13NO3
AppearanceClear Light Yellow Oil
Melting PointN/A
Molecular Weight171.19
StorageRefrigerator
SolubilityChloroform (Slightly), Methanol (Slightly)
Category Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsN-Carbethoxy-4-piperidone (Loratadine EP Impurity H) is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. N-Carbethoxy-4-piperidone is also an impurity of Loratadine (L469575).
ReferencesSchenker, E. et al.: Arsneim.-Forsch., 29, 1835 (1979); El-Kader, A. et al.: Mans. J. Pharm. Sci., 6, 1 (1989); Albu, M. et al.: J. Liq. Chrom. Rel. Technol., 32, 2569 (2009);