C175820 Chemical Structure

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C175820

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Product Description

Catalogue NumberC175820
Chemical NameCarbazochrome
Synonyms2-(1,2,3,6-Tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide; 3-Hydroxy-1-methyl-5,6-indolinedione 5-Semicarbazone; Adrenochrome Semicarbazone; Adchnon; Adedolon; Adrenochrome Monosemicarbazone; Adrenostazin; Adrenoxyl; Adrezon; Adrokson; Adroxon; Carbazochrom; Cartabes; Cromadrenal; Cromosil; NSC 73742; Sangostasin; Sangostazin
CAS Number69-81-8
Molecular FormulaC10H12N4O3
AppearanceDark Orange to Very Dark Orange Solid
Melting Point>206°C (dec.)
Molecular Weight236.23
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityDMSO (Slightly), Water (Slightly, Heated)
StabilityHygroscopic
Category Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsCarbazochrome is an oxidation product of Epinephrine [E588580]) that improves microcirculatory tone. Derivatives such as carbazochrome salicylate and carbazochrome sodium sulfonate, are used as hemostats and treatment to prevent dengue shock syndrome, respectively.
ReferencesBasile, M., et al.: Curr. Ther. Res., 63, 527 (2002); McLean, W. & Campolongo, J.: Can. J. Surg., 16, 333 (1973); Tassniyom, S., et al.: J. Ped., 131, 525 (1997)