C175195 Chemical Structure

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C175195

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Product Description

Catalogue NumberC175195
Chemical Name(-)-Canadalisol
Synonyms2,3-Dimethoxy-6-[[(5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]methyl]benzenemethanol; (S)-1,3-Dioxolo[4,5-g]isoquinoline Benzenemethanol Deriv.;
CAS Number123878-19-3
Molecular FormulaC₂₁H₂₅NO₅
Molecular Weight371.43
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(-)-Canadalisol is a synthetic analogue of S-(-)-Canadine (C175175), a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons.
ReferencesHanaoka, M., et al.: Heterocycles., 29, 221 (1989);