Catalogue number: C175180
Chemical name: (S)-(-)-Canadine
Synonyms: (S)-5,8,13,13a-tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine; Canadine; (-)-Canadine; (-)-Tetrahydroberberine; (-)-α-Canadine; (S)-(-)-7,8,13,13a-Tetrahydroberberine; (S)-(-)-Tetrahydroberberine; (S)-Canadine; (S)-Tetrahydroberberine; 9,10-Dimethoxy-2,3-(methylenedioxy)-13aα-berbine; l-Canadine; α-Canadine
CAS Number: 5096-57-1
Alternate CAS #: NA
Molecular form.: C₂₀H₂₁NO₄
Appearance: Pale Yellow to Light Yellow Solid
Melting Point: 132-134°C
Mol. Weight: 339.39
Storage: Refrigerator
Solubility: Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated)
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.
Dangerous Goods Info: NA

All Products are stable to be shipped at room temperature, unless otherwise specified.
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