C143465 Chemical Structure

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1mg
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5mg
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10mg
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C143465

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Product Description

Catalogue NumberC143465
Chemical Name((4-(7-(2-(4-Chlorophenoxy)ethyl)-2-(methylamino)-6-oxo-6,7-dihydro-3H-purin-8-yl)phenyl)difluoromethyl)phosphonic Acid
CAS Number1373822-46-8
Molecular FormulaC₂₁H₁₉ClF₂N₅O₅P
Molecular Weight525.83
Category Building Blocks; Miscellaneous;
Applications((4-(7-(2-(4-Chlorophenoxy)ethyl)-2-(methylamino)-6-oxo-6,7-dihydro-3H-purin-8-yl)phenyl)difluoromethyl)phosphonic Acid is used as an intermediate in the synthesis of guanine-derived inhibitors of eIF4E mRNA-cap interaction.
ReferencesChen, X., et al.: J. Med. Chem., 55, 3837 (2012)